IRF Projects 2011

The IRF projects for ISCOMS 2011 are the following:

Project A: Modulating cholesterol excretion to interfere with atherosclerotic cardiovascular disease
Department of Pediatrics - Center for Liver, Digestive and Metabolic Diseases (CLDS)
Coordinator: Prof. U.J.F. Tietge, PhD

Project B: The role of miR146a in Rheumatoid Arthritis
Department of Rheumatology and Clinical Immunology
Coordinator: B.J. Kroesen, PhD

Project C: Malaria vaccination – cost-effectiveness and impact on blood safety and blood transfusion
Department of Transfusion Medicine
Coordinator: Prof. C.Th. Smit Sibinga, MD PhD FRCP Edin FRCPath
Department of Pharmacy, Unit of Pharmacoepidemiology and -economics
Coordinator: Prof. M.J. Postma, PhD

Project D: Effects of small molecules on differentiation during Hematopoietic Stem Cell expansion cultures.
Department of Stem Cell Biology
Coordinators: Prof. G. de Haan, MD PhD, R. van Os, MD PhD

Project E: Validation of a prediction model for deterioration of disease in women with pregnancy induced hypertension or mild pre-eclampsia at term.
Departments of Epidemiology and Obstetrics & Gynecology
Coordinators: H. Groen, MD PhD and K. van der Tuuk, MD

Project F: Implementation of the genetic background in the pathogenesis of inflammatory bowel disease
Department of Internal Medicine-Gastrointestinal & Hepatic Disorders
Coordinators: S. van Sommeren, MD/PhD student, K. Fransen, MD/PhD student

Project G: Life and death in the chronically injured liver
Department of Gastroenterology and Hepatology
Coordinators:  Prof. H. Moshage PhD, Prof. K.N. Faber PhD

Project H: HSP-inducer GGA as a new drug against cardiac arrhythmia
Department of Cardiology and Clinical Pharmacology
Coordinators: Bianca Brundel, MD PhD, Irma Kuipers, MD and Femke Hoogstra-Berends

Project I: Chipping away at the genetics of cardiovascular disease
Department of Cardiology
Coordinator: P. van der Harst, MD PhD

Project J: Curing the heart with fat stem cells
Department of Pathology & Medical Biology - Cardiovascular Regenerative Medicine Res.Grp. (CAVAREM)
Coordinators: M.C.Harmsen PhD, E. Przybyt MSc

Project K: Pulsatile vs. non-pulsatile cardio pulmonary Bypass
Department of Biomedical engineering, Materials Science and Application (BMSA)
Coordinator: Prof. G. Rakhorst DVM PhD

Project L: Systemic autoimmune disease: the role of regulatory B cells
Department of Pathology and Medical Biology
Coordinator: Prof. P. Heeringa PhD
In collaboration with the department of Rheumatology and Clinical Immunology (Prof. dr. C.G.M. Kallenberg, Dr. A. Rutgers)

Project M: Ideal timing of protective ARA 290 treatment following renal transplantation
Department of Surgery
Coordinator: H. Leuvenink MD PhD, W.G. van Rijt PhD student
Department of Pathology
Coordinator: Prof. H. van Goor MD PhD

Project N: Kidney Center
Department of Internal Medicine, Nephrology (GUIDE)
Coordinator: Prof. G.J. Navis MD PhD

Project O: Antihemostatic therapy to alleviate acetaminophen-induced acute liver injury
Department of Surgery, Surgical Research Laboratory
Coordinator: Prof. Ton Lisman MD PhD

Project P: The physiological role of brain microglia
Department of Neuroscience and Medical Physiology
Coordinator: Prof. Hendrikus W.G.M. Boddeke MD PhD, drs D. rai